Researchers Identify Potential Antibody-based Myeloma Therapy

Researchers in Japan have identified an antibody that binds to a myeloma-specific form of a common cell surface protein, called CD98 heavy chain, and that prolongs survival when given to a mouse model of multiple myeloma. The findings were detailed in the study, “Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the ubiquitous protein CD98 heavy chain,” published in Science Translational Medicine. “Despite the CD98 heavy chain being present on all cells,…

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