This post was originally published on this site Eureka Therapeutics is planning a Phase 1/2 clinical trial in the United States to explore the safety and effectiveness of its investigational T-cell therapy ET140202 in patients with advanced hepatocellular carcinoma (HCC), the most common form of liver cancer. The announcement comes after the U.S. Food and…
This post was originally published on this site While my doctor’s fingers massaged my breasts and cradled my hard, almond-sized lump, we had a peculiar conversation. She was from the Bay Area but traveled to tiny Lakeport for a brief assignment. My husband and I discovered the lump the previous evening in a surprising, romance-busting…
This post was originally published on this site Reducing the interval between chemotherapy treatment cycles or administering chemotherapy medications sequentially at higher doses, rather than simultaneously at lower doses, increases treatment efficacy and decreases the risk of breast cancer recurrence and death, a study suggests. The study, “Increasing the dose intensity of chemotherapy by more…
This post was originally published on this site Plerixafor — approved for the treatment of lymphoma and multiple myeloma — decreases tumor fibrosis and improves immunotherapy response in a mouse model of metastatic breast cancer, a study finds. The study, “Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer,” was published…
This post was originally published on this site More than 600 young breast cancer survivors will gather in Austin, Texas, for the 4th Annual Young Survival Coalition (YSC) Summit. For such survivors, it’s the only national conference. In addition to those diagnosed with breast cancer before their 41st birthday, the March 8-10 YSC-sponsored event targets “co-survivors”…
This post was originally published on this site By targeting small regulatory molecules called microRNAs (miRNAs), researchers were able to reprogram breast cancer cells and render them sensitive to HER2-targeting medicines, such as Herceptin (trastuzumab) and Kadcyla (ado-trastuzumab emtansine), a study shows. The study, “A Designed Small Molecule Inhibitor of a Non-Coding RNA Sensitizes HER2 Negative Cancers to…
This post was originally published on this site According to a review study published in Frontiers in Pharmacology, dietary plant-based molecules that possess antioxidant properties called polyphenols can aid in the management of benign prostatic hyperplasia (BPH). However, these compounds cannot replace the need for existing therapies, surgical or pharmacological, as an effective treatment of this condition.…
This post was originally published on this site In a recent study, a team of researchers found a new compound that can be administered as eye drops and partly reversed cataracts in a mice model. The study, “Pharmacological chaperone for α-crystallin partially restores transparency in cataract models,” was published in the journal Science. Cataracts are the most common cause of…
This post was originally published on this site Hispanic-American patients with Alzheimer’s disease tend to live significantly longer after disease onset and with milder cognitive decline than African-Americans and non-Hispanic whites, a study reports. The study, “Ethnoracial differences in Alzheimer’s disease from the FLorida Autopsied Multi-Ethnic (FLAME) cohort,” was published in the journal Alzheimer’s &…
This post was originally published on this site According to new guidelines from the American Academy of Pediatrics (AAP), a two-fold simple approach could be used to prevent teenage obesity and eating disorders. The report “Preventing Obesity and Eating Disorders in Adolescents,” published in the journal Pediatrics, advises that parents and health experts should veer from focusing…
