This post was originally published on this site Many patients with blood cancers, such as myeloma, go into remission after receiving a stem-cell transplant. However, there are still many patients (about one-third) who relapse, a condition usually associated with a poor prognosis. Dana-Farber Cancer Institute researchers tested the effects of a new treatment approach using repeated doses of the immunotherapy drug Yervoy…
This post was originally published on this site AstraZeneca is presenting a broad selection of its novel respiratory disease medicines through more than 60 abstracts and scientific presentations at the American Thoracic Society (ATS) 2016 International Conference through May 18 in San Francisco, Calif. Presentations highlight combinations, respiratory biologics, and scientific research projects that target new…
This post was originally published on this site Radiotherapy after breast cancer surgery that’s limited to former tumor sites is just as effective in treating early cancers as whole breast radiation and has fewer long-term side effects, according to results of a clinical study presented at the recent 10th European Breast Cancer Conference. The trial, called IMPORT LOW and supported…
This post was originally published on this site Elotuzumab in combination with bortezomib and dexamethasone prolongs the progression free survival of patients with relapsed or refractory multiple myeloma (RRMM), according to the study “Randomized phase 2 study of elotuzumab plus bortezomib/dexamethasone (Bd) versus Bd for relapsed/refractory multiple myeloma,” recently published in Blood. Current choices of care for the treatment…
This post was originally published on this site A three-drug combination that includes thalidomide, in place of cyclophosphamide, prior to an autologous stem cell transplant was seen to improve response rates in multiple myeloma patients, according to the conclusions of a randomized, open-label Phase 3 trial, titled “VTD is superior to VCD prior to intensive therapy in multiple…
This post was originally published on this site The U.S. Food and Drug Administration has designated Darzalex (daratumumab), in combination with standard-of-care regimens, a breakthrough therapy for people with previously treated multiple myeloma (MM), speeding its clinical development and regulatory review for these patients. The FDA designation is reserved for treatments showing early evidence in clinical studies of substantial improvement over existing therapies. Darzalex…
This post was originally published on this site A randomized Phase 3 clincal trial has concluded that combining bortezomib (Velcade) with pegylated liposomal doxorubicin (PLD) does not show benefit in treating relapsed or refractory multiple myeloma (MM) patients, compared to bortezomib alone. The data was published in Cancer under the title “Final overall survival results of a randomized…
This post was originally published on this site The FDA published the approval of the first focused ultrasound device for the treatment of essential tremor in people who did not respond to treatment. Magnetic resonance (MR) images are taken by ExAblate Neuro during application of focused ultrasound to kill the brain cells which are considered…
This post was originally published on this site World neurosurgery leaders gathered in Amsterdam May 15-19 for the 18th International Leksell Gamma Knife Society Meeting. The annual conference is dedicated to Gamma Knife surgery in the treatment of intracranial disorders, and covers topics such as radiosurgery, benign tumors, vascular disorders, malignant tumors, ophthalmological disorders, functional…
This post was originally published on this site A combination of Bristol-Myers Squibb’s immune checkpoint inhibitors Opdivo (nivolumab) and Yervoy (ipilimumab) reduces tumor burden in castration-resistant prostate cancer patients whose tumors have spread, interim Phase 2 results show. Findings from the CheckMate 650 trial (NCT02985957) were recently shared at the 2019 Genitourinary Cancers Symposium in San Francisco in a presentation…
