This post was originally published on this site A gene associated with a rare balance disorder also may be involved in susceptibility to Alzheimer’s disease, a new study in mice shows. The study, “Loss of Ataxin-1 Potentiates Alzheimer’s Pathogenesis by Elevating Cerebral BACE1 Transcription,” was published in the journal Cell. Mutations that affect a gene’s function…
Category: Alzheimer’s
Our Family’s Golden Retriever Is More Than Man’s Best Friend
This post was originally published on this site This week, pet lovers across the United States celebrated National Dog Day to bring awareness to the thousands of dogs that need rescuing. My golden retriever is celebrated every day. A last act of love Jack isn’t an official service dog, but he is a helper to…
3D Model Unravels How Beta-amyloid Weakens Brain-Blood Barrier, May Aid in Treatment Discovery
This post was originally published on this site A new 3D model using human cells grown on a chip can mimic what happens in the brain during Alzheimer’s and allow for the screening of possible therapies in a disease where so many fail, including medicines already approved for other conditions. This tissue model also helps…
Understanding Protein Aggregation May Aid Quest for Better Alzheimer’s Treatments
This post was originally published on this site Better understanding the mathematics behind how protein clumps form — and how therapies interfere with this process — may improve treatment strategies for Alzheimer’s, and other diseases, new research suggests. The study, “Optimal control strategies for inhibition of protein aggregation,” was published in PNAS. Protein aggregation is the term…
Managing Caregiver Stress in AD Essential During Back-to-School Time, AFA Says
This post was originally published on this site The strain of caring for someone with Alzheimer’s disease (AD) during the hectic back-to-school season can be overwhelming. For good brain health, the Alzheimer’s Foundation of America (AFA) says it’s essential to take measures to mitigate stress. “It’s super important to make managing stress one of your…
Finding the Motivation to Avoid the ‘Caregiving Slump’
This post was originally published on this site Life doesn’t come to a screeching halt while you care for a person who has Alzheimer’s disease. Time marches on for familial caregivers. There is a certain fluidity to life. We want to go with the flow, but it is difficult as we swim against the current.…
Diet Rich in Choline Aids Memory and Lowers Risk of Dementia, Study Suggests
This post was originally published on this site A diet rich in phosphatidylcholine, a form of the choline found in foods like eggs and meat, was linked to a lower risk of dementia and better memory skills in middle-aged men in Finland, a recent study reports. These findings suggest that choline helps to support cognitive processing, and…
FDG PET Scan More Accurately Assesses Severity of Cognitive Decline in Alzheimer’s, Study Finds
This post was originally published on this site Compared to regular amyloid imaging, fluorodeoxyglucose positron emission tomography (FDG PET), an imaging technique that quantifies brain function by measuring glucose levels, can better assess the progression and severity of cognitive decline in people with Alzheimer’s, and also cognitive impairment, researchers have found. Their study, “18F-FDG Is…
Middle-Age Adults With High Blood Pressure at Greater Risk of Dementia, Study Suggests
This post was originally published on this site People with high blood pressure, or hypertension, during midlife are at a greater risk of developing dementia, irrespective of their blood pressure later on, a long-term follow-up study suggests. The study, “Association of Midlife to Late-Life Blood Pressure Patterns With Incident Dementia,” was published in the Journal…
Caregiving Tasks Fluctuate between Urgent and Necessary
This post was originally published on this site One of the greatest privileges of my life was to care for my mother, who had Alzheimer’s disease. However, I was constantly fighting an internal battle. A feeling of inadequacy always bubbled beneath the surface. Many caregivers fight similar battles. This is why I wrote the following,…