This post was originally published on this site Virtual reality may help improve the quality of life for people with dementia, including those with Alzheimer’s disease, by stimulating them to recall past memories, reduce aggressive behavior, and connect with caregivers, a study suggests. The study, “Bring the Outside In: Providing Accessible Experiences Through VR for…
Category: Alzheimer’s
Tips to Help Members of the Sandwich Generation Balance Responsibilities
This post was originally published on this site The sandwich generation is one of the many terms that define caregiving. As you can guess, the term has nothing to do with two pieces of bread spread with peanut butter and jelly. Rather, the sandwich generation refers to those who currently are raising children or supporting…
Antibodies That Target Neurotoxic Proteins in Alzheimer’s Are Identified
This post was originally published on this site ProMIS Neurosciences researchers have discovered new antibody candidates that selectively bind to the neurotoxic form of the tau protein — one of the hallmarks of Alzheimer’s disease. These new antibodies join the company’s PMN310, a humanized antibody that attacks only toxic forms of the amyloid beta protein…
Early Brain Alterations May Occur Decades Before Onset of First Symptoms, Researchers Say
This post was originally published on this site Scientists have found a series of brain alterations associated with Alzheimer’s disease that occur decades before the onset of the first symptoms. Identifying these biological and anatomical brain alterations in people at high-risk for the disease may help them receive earlier therapeutic interventions, the researchers said. The study,…
The Death of Denial
This post was originally published on this site I was helping Mom in the bathroom when suddenly she slumped over, unable to hold herself upright. Her hospice nurse was scheduled to come later that day but had previously offered to come sooner if needed, so I immediately contacted her. As soon as she saw Mom, she…
More than a Million Children Provide Familial Care in the US
This post was originally published on this site The most recent statistics surrounding family caregiving in the United States are staggering. A 2005 National Alliance for Caregiving report estimates that 65.7 million Americans are familial caregivers. Of that number, more than 16 million care for people with dementia or Alzheimer’s disease. Shockingly, some of those…
ADDF Grants $1.5M to Fund U.S. Arm of Phase 2a Trial for Vafidemstat in Alzheimer’s Patients
This post was originally published on this site The Alzheimer’s Drug Discovery Foundation (ADDF) has awarded $1.5 million to Oryzon Genomics to support expanding an ongoing Phase 2a trial assessing the potential of vafidemstat (ORY-2001) in patients with mild to moderate Alzheimer’s disease to the United States. The double-blind, placebo-controlled trial (2017-004893-32), called ETHERAL, is…
PRI-002, Oral Therapy Candidate for Alzheimer’s, Deemed Safe in Phase 1 Trial
This post was originally published on this site Alzheimer’s oral therapy candidate PRI-002, being developed by Priavoid, has proven safe for human use in healthy volunteers during a Phase 1 clinical trial. These positive trial results provide important evidence that supports progressing PRI-002 into studies of patients who have Alzheimer’s disease. “Our next goal is the…
Investigational Alzheimer’s Therapy NNI-362 Receives FDA Approval to Enter Phase 1 Clinical Studies
This post was originally published on this site The U.S. Food and Drug Administration has approved Neuronascent’s investigational new drug (IND) application for NNI-362, its therapy candidate for Alzheimer’s disease, allowing it to move ahead with a Phase 1a clinical trial, the company announced. The first-in-human trial will evaluate the safety of NNI-362 in healthy…
Caregivers Can Help Preserve Alzheimer’s Patients’ Dignity
This post was originally published on this site Dignity diminished Alzheimer’s disease has a way of robbing a person’s dignity. Given enough time, it strips away what is basic to our loved one’s personality, including the very characteristics associated with dignity. It replaces their normal reserve, appearance, language, and seriousness of manner with odd behavior…