This post was originally published on this site Syntrix Pharmaceuticals has dosed the first patient in an ongoing Phase 1/2 clinical trial testing its experimental therapy SX-682 in combination with Keytruda (pembrolizumab) as a treatment for advanced melanoma, the company announced. The open-label trial (NCT03161431) is being conducted at the Massachusetts General Hospital Cancer Center and…
About Cancer
Cancer, also called malignancy, is an abnormal growth of cells with the potential to invade or spread to surrounding tissues and structures found within the body. There are more than 100 types of cancer. A few examples include breast cancer, skin cancer, lung cancer, colon cancer, prostate cancer, and lymphoma. According to the American Cancer Society, 4 out of 10 people will be diagnosed with some form of cancer in their lifetime. Cancer prevalence has given rise to multiple medical specialties focused on symptom management and disease management. Current treatment options depending on the form of cancer include chemotherapy, radiation, blood or bone marrow transfusions, and/or surgery. Lifetime prognosis of cancer mortality is dependent on the type of cancer and is heavily conditional to early detection.
Conditions
Cancer News
Combining Breast, Lung Cancer Therapies Could Overcome Treatment Resistance
This post was originally published on this site Combining Ibrance (palbociclib), a treatment for advanced breast cancer, with the lung cancer medicine crizotinib is more effective against human cancer cells in the laboratory than either drug alone, scientists have found. The researchers say the findings suggest the combination could be used to overcome treatment resistance in some…
Video Series Tackles Prostate Cancer and ADT Use in Doctor-Patient Format
This post was originally published on this site CURE Media Group has introduced a video discussion series on topics of concern to prostate cancer patients, including cardiovascular risk management and androgen deprivation therapy (ADT). Called “ADT in Prostate Cancer: Managing Cardiovascular Risk,” the nine-episode series features Andy Rochester, a prostate cancer survivor, discussing his experiences with Susan F.…
Collaborative Project Aims to Improve Care for Advanced Ovarian Cancer Patients
This post was originally published on this site A new collaborative project seeks to help ovarian cancer programs better understand and remove impediments to optimal care for patients with advanced epithelial disease. Called “Barriers to Quality Care in Ovarian Cancer,” the effort will be led by the Association of Community Cancer Centers (ACCC), along with AstraZeneca…
Adding Darzalex to a Velcade-Revlimid Combo Boosts Cancer Disappearance in Newly Diagnosed Multiple Myeloma, Phase 2 Trial Shows
This post was originally published on this site Adding Darzalex (daratumumab) to a treatment combination of Velcade (bortezomib), Revlimid (lenalidomide), and dexamethasone increased the proportion of newly diagnosed patients with multiple myeloma showing complete cancer disappearance, according to top-line results of a Phase 2 clinical trial. The open-label GRIFFIN study (NCT02874742) includes 223 patients eligible for high-dose chemotherapy…
NantKwest Launches Phase 1 Trial to Assess Investigational Cell Therapy for B-cell Lymphomas
This post was originally published on this site NantKwest is launching the first-in-human Phase 1 clinical trial assessing the effects of its investigational CD19 t-haNK cell therapy in people with locally advanced B-cell lymphoma. The trial follows the U.S. Food and Drug Administration‘s approval of NantKwest’s investigational new drug (IND) application for the therapy. Natural…
PrimeVax Receives FDA’s OK to Use Dengue Virus for Cancer Treatment
This post was originally published on this site The U.S. Food and Drug Administration (FDA) has approved three clinical studies testing PrimeVax Immuno-Oncology’s investigational approach using dendritic cells and dengue virus for cancer treatment. The investigational new drug (IND) application is for patients with melanoma (skin cancer) who have failed prior immune checkpoint inhibitors. Hospital…
Breast Cancer? Put It on Ice
This post was originally published on this site The bad news? It was cancer. The good news? It was in the early stages, a baby tumor at 1.5 cm. It’s hard to believe something so small has such a big impact. My friend Lauren went to a routine mammogram and was surprised when she heard…
MSN Labs to Launch Generic Version of Zytiga in U.S. Following FDA Approval
This post was originally published on this site MSN Labs, the parent company of Novadoz Pharmaceuticals, is launching a generic version of Janssen Pharmaceuticals’ approved therapy Zytiga (abiraterone acetate) in the U.S. market. Following its approval by the U.S. Food and Drug Administration (FDA), the generic abiraterone acetate 250mg tablets will be available for the…
Older Sarcoidosis Patients Have Worse Disease, Outcomes, Study Suggests
This post was originally published on this site According to a new study comparing older and younger sarcoidosis patients, elderly people with sarcoidosis tend to have more severe disease and worse clinical outcomes. The study, “Elderly sarcoidosis: A comparative study from a 42-year single-centre experience,” was published in the journal Respiratory Medicine. Sarcoidosis usually presents in…
Making It Over the Metaphorical Mountain
This post was originally published on this site There is a popular maxim that reads, “Things often get worse before they get better.” It’s one applied to various scenarios in life, but for those of us going through treatment for cancer, it means getting sicker in order to finally get better. This applies especially to…
Antibody-Drug Conjugate Shows Efficacy in Heavily Treated Cancers
This post was originally published on this site An investigational antibody-drug conjugate made of the HER2-targeting antibody trastuzumab (marketed as Herceptin and others) attached to a kind of chemotherapy compound has demonstrated notable efficacy in heavily treated patients with breast and other cancer types, a Phase 1 trial showed. “Trastuzumab duocarmazine in locally advanced and…