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Bayer, Orion Seek Darolutamide’s Approval in Europe for Non-metastatic CRPC

Bayer, Orion Seek Darolutamide’s Approval in Europe for Non-metastatic CRPC

This post was originally published on this site Bayer and Orion have successfully submitted an application to the European Medicines Agency seeking the approval of darolutamide for men with non-metastatic castration-resistant prostate cancer (nmCRPC). The application follows promising results from the ARAMIS Phase 3 trial (NCT02200614), where a combination of darolutamide and androgen deprivation therapy (ADT) delayed cancer spread by 22 months, compared to…

PD-L1 Levels, Response to Tecentriq Linked in Younger Cancer Patients

PD-L1 Levels, Response to Tecentriq Linked in Younger Cancer Patients

This post was originally published on this site Children, adolescents, and young adults with relapsed or refractory cancers — particularly those with lymphoma — have better responses to Genentech‘s immune checkpoint inhibitor Tecentriq (atezolizumab) if they have high levels of the PD-L1 factor in their tumors, a study found. The findings will be presented during…

NBA’s Atlanta Hawks Raises $150K for Prostate Cancer Awareness and Research

NBA’s Atlanta Hawks Raises $150K for Prostate Cancer Awareness and Research

This post was originally published on this site An inaugural effort by the Atlanta Hawks to help defeat prostate cancer by raising awareness and funds for important research netted $150,000 for the Prostate Cancer Foundation (PCF). The NBA basketball team’s drive was launched in February during African-American History Month to bring greater awareness of the disorder to…

Biogen and Eisai Halt Phase 3 Trials Testing Aducanumab for Early Alzheimer’s

Biogen and Eisai Halt Phase 3 Trials Testing Aducanumab for Early Alzheimer’s

This post was originally published on this site Two Phase 3 clinical trials testing the investigational therapy aducanumab in patients with early Alzheimer’s disease have been discontinued. Biogen and Eisai came to this decision after an analysis from an independent data monitoring committee indicated that the global ENGAGE (NCT02477800) and EMERGE (NCT02484547) studies of aducanumab…

AI Matches Radiologists’ Skill at Detecting Breast Cancer on Mammograms

AI Matches Radiologists’ Skill at Detecting Breast Cancer on Mammograms

This post was originally published on this site An artificial intelligence (AI) system based on deep learning algorithms is able to detect breast cancer in digital mammography screenings as well as experienced radiologists, a study says. The findings of the study, “Stand-Alone Artificial Intelligence for Breast Cancer Detection in Mammography: Comparison With 101 Radiologists,” were…

FDA Approves Tecentriq/Chemo for Newly Diagnosed Extensive-stage SCLC

FDA Approves Tecentriq/Chemo for Newly Diagnosed Extensive-stage SCLC

This post was originally published on this site The U.S. Food and Drug Administration has approved the use of Tecentriq (atezolizumab) in combination with the chemotherapies Paraplatin (carboplatin) and etoposar for the initial treatment of extensive-stage small-cell lung cancer patients. The approval, which makes Tecentriq the first immunotherapy approved for this indication, is based on findings…

Scotland Rejects NHS Access to Kymriah for Aggressive Diffuse Large B-cell Lymphoma

Scotland Rejects NHS Access to Kymriah for Aggressive Diffuse Large B-cell Lymphoma

This post was originally published on this site Scotland’s healthcare system has rejected the use of Novartis‘ immunotherapy Kymriah (tisagenlecleucel) for adults with aggressive diffuse large B-cell lymphoma (DLBCL) who failed at least two prior lines of therapy.  The Scottish Medicines Consortium (SMC) denied routine access to Kymriah through NHS Scotland based on “uncertainties in the company’s evidence around its…

Darzalex Triple Combo Approved in England for Difficult-to-treat Multiple Myeloma

Darzalex Triple Combo Approved in England for Difficult-to-treat Multiple Myeloma

This post was originally published on this site A triple combination of Darzalex (daratumumab), Velcade (bortezomib), and dexamethasone will be available on the National Health Service (NHS) in England for the treatment of relapsed or refractory multiple myeloma patients. The U.K.’s National Institute of Health and Care Excellence (NICE) decided to approve the therapy based on…

Low White Blood Cell Count May Help Predict Some Ovarian Cancer Outcomes

Low White Blood Cell Count May Help Predict Some Ovarian Cancer Outcomes

This post was originally published on this site A reduced number of lymphocytes — one of the main types of immune cells — in advanced ovarian cancer patients before treatment is linked with a higher risk of disease worsening and shorter overall survival, according to a South Korean study. The study, “Pretreatment lymphocytopenia is an…