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New Imaging-Guided System Helps Surgeons Remove Tiny Ovarian Tumors

New Imaging-Guided System Helps Surgeons Remove Tiny Ovarian Tumors

This post was originally published on this site A new imaging-guided surgical technique that makes ovarian cancer tumors glow under near-infrared light can help surgeons remove tumors as small as 0.3 millimeters, a study in mice shows. The approach also increased mice’s lifespan by 40% compared to mice treated with standard non-imaging-guided surgery. Researchers are…

#AANAM – Memantine as Add-on Therapy Seen to Ease Psychosis, Other Advanced Alzheimer’s Symptoms

#AANAM – Memantine as Add-on Therapy Seen to Ease Psychosis, Other Advanced Alzheimer’s Symptoms

This post was originally published on this site Adding memantine to a cholinesterase inhibitor can significantly ease certain neuropsychiatric symptoms, including psychosis and troubling motor or nighttime behavior, in people with moderate-to-severe Alzheimer’s disease, according to pooled data from three Phase 3 clinical trials. But it was not seen to be of any benefit in…

SHARE Introduces My MBC & Me App for Metastatic Breast Cancer Patients

SHARE Introduces My MBC & Me App for Metastatic Breast Cancer Patients

This post was originally published on this site Since her diagnosis of metastatic breast cancer two years ago, Karen Peterson has been amid a whirlwind of medical appointments and healthcare professionals. It’s often overwhelming. “Managing it all is like a job,” the 54-year-old New York City resident said in an interview with Breast Cancer News.…

Kyprolis Combo Shows Promise for Newly Diagnosed, Transplant-eligible Patients

Kyprolis Combo Shows Promise for Newly Diagnosed, Transplant-eligible Patients

This post was originally published on this site A triple regimen composed of Kyprolis (carfilzomib), thalidomide, and dexamethasone, given before and after high-dose chemotherapy and autologous stem cell transplant, is safe and highly effective for the treatment of newly diagnosed multiple myeloma, results of a Phase 2 clinical trial show. The study, “Phase 2 Study…

Janssen Seeks Expanded FDA Approval of Erleada to Treat Metastatic Castration-sensitive Prostate Cancer

Janssen Seeks Expanded FDA Approval of Erleada to Treat Metastatic Castration-sensitive Prostate Cancer

This post was originally published on this site Janssen has submitted an application with the U.S. Food and Drug Administration (FDA) seeking the approval of its androgen receptor inhibitor Erleada (apalutamide) for patients with metastatic castration-sensitive prostate cancer (CSPC). The supplemental new drug application is based on data from the ongoing Phase 3 TITAN clinical trial…

Recent Immunosuppression, Persistently High HIV Load Predict Lymphoma Risk

Recent Immunosuppression, Persistently High HIV Load Predict Lymphoma Risk

This post was originally published on this site Recent immunosuppression, which causes a drop in CD4 T-cell levels, and prolonged exposure to high HIV viral load are two independent predictors of non-Hodgkin’s lymphoma among people living with HIV, a recent study shows. While these two measures also predicted the risk of diffuse large B-cell lymphoma (DLBCL)…

Gritstone to Move Slate Immunotherapy into Clinical Trial Sooner than Anticipated

Gritstone to Move Slate Immunotherapy into Clinical Trial Sooner than Anticipated

This post was originally published on this site Gritstone Oncology is advancing its investigational immunotherapy Slate into Phase 1 clinical studies sooner than planned, and expects patient enrollment to start as early as mid-2019, the company announced. This follows feedback from the U.S. Food and Drug Administration (FDA), which will review toxicity data from Granite…

Allogene’s CAR T-cell Therapy Triggers Durable Anti-Tumor Response in Animal Model

Allogene’s CAR T-cell Therapy Triggers Durable Anti-Tumor Response in Animal Model

This post was originally published on this site ALLO-715, Allogene Therapeutics‘ donor-derived CAR T-cell therapy, can trigger a durable anti-tumor response in mice with multiple myeloma, and maintain its characteristics and anti-tumor activity after large-scale manufacturing, a study says. The preclinical findings were reported in the study, “Preclinical Evaluation of Allogeneic CAR T Cells Targeting BCMA…

Lynparza Recommended for Approval in Europe for BRCA-mutated Advanced OC

Lynparza Recommended for Approval in Europe for BRCA-mutated Advanced OC

This post was originally published on this site The Committee for Medicinal Products for Human Use (CHMP), an arm of the European Medicines Agency (EMA), has recommended that Lynparza (olaparib) be approved as a first-line maintenance therapy for women with BRCA-mutated advanced ovarian cancer, AstraZeneca and Merck announced. Specifically, the recommendation is for women who are responding, partially or completely,…