This post was originally published on this site A diet that is high in salt can cause dementia in mice by promoting a buildup of plaques of the protein tau, which is also associated with Alzheimer’s disease, a new study shows. The study, titled “Dietary salt promotes cognitive impairment through tau phosphorylation,” was published in Nature.…
Conditions
Conditions
Hormone Therapy Has More Long-term Impact on Quality of Life Than Chemo, Study Suggests
This post was originally published on this site Challenging conventional wisdom, new findings suggest that hormone therapy may have a greater impact than chemotherapy on long-term quality of life in women with breast cancer, particularly those who have gone through menopause. The study, “Differential impact of endocrine therapy and chemotherapy on quality of life of…
Tecentriq-Avastin Prolongs Life of Patients with Advanced Liver Cancer in Trial, Roche Reports
This post was originally published on this site A combination of Tecentriq (atezolizumab) and Avastin (bevacizumab) extends overall survival and the time lived without disease progression in people with newly-diagnosed, inoperable hepatocellular carcinoma (HCC), the most common type of liver cancer, compared to standard-of-care treatment with Nexavar (sorafenib), results from the IMbrave150 Phase 3 trial…
Nothing but Mammals: How Cancer Affects Sexual Health
This post was originally published on this site This week, I want to dive into a topic that’s not always at the top of the list during one’s oncology appointments. Yet it’s something that most of us do regularly (or at least we’d like to be) and it’s something that — surprise, surprise — cancer…
Darzalex Combo Approved in Canada for Newly Diagnosed Myeloma Patients Ineligible for Transplant
This post was originally published on this site Health Canada has approved Darzalex (daratumumab), in combination with standard Revlimid (lenalidomide) and dexamethasone, for people newly diagnosed with multiple myeloma who are not eligible for an autologous stem cell transplant. Under priority review, the approval was based on data from the Phase 3 MAIA trial (NCT02252172), in which…
OTL38 ‘Lights up’ Ovarian Cancer Cells, Helping Surgeons to Remove Them, Phase 2 Study Shows
This post was originally published on this site OTL38, a tumor-specific fluorescent compound that “lights up” ovarian tumor tissue during surgery, helped doctors to detect and remove cancer cells that would otherwise be missed, final results of a Phase 2 study show. The study, “A phase II, multicenter, open-label trial of OTL38 injection for the…
Seaweed-based Therapy Approved in China for Mild to Moderate Alzheimer’s, 1st New Treatment in 16 Years
This post was originally published on this site Oligomannate (GV-971), a compound derived from marine brown algae that promotes a healthy gut microbiome, is now conditionally approved in China to treat mild to moderate Alzheimer’s disease (AD), making it the first new disease therapy approved anywhere since Allergan’s Namenda (memantine) in late 2003. The decision was…
Alzheimer’s Awareness Month in US Focuses on Caregivers, Resources and Education
This post was originally published on this site Efforts are underway this month to focus attention on Alzheimer’s (AD), a disease that, along with other forms of dementia, affects some 44 million people globally and is rapidly growing in prevalence. During November in the U.S., Alzheimer’s Awareness Month observances include online tributes to caregivers, listings of…
Nektar Launches Phase 1 Trial Testing NKTR-255 in Non-Hodgkin’s Lymphoma, Multiple Myeloma
This post was originally published on this site Nektar Therapeutics is launching a first-in-human Phase 1 clinical trial assessing the safety and efficacy of its investigational agent NKTR-255 in people with relapsed or refractory non-Hodgkin’s lymphoma and multiple myeloma. The study (NCT04136756) is recruiting up to 82 patients across multiple U.S. sites and also will…
Transbronchial Lung Cryobiopsy Helps Provide Definitive Diagnose of Sarcoidosis, Study Suggests
This post was originally published on this site Transbronchial lung cryobiopsy — a relatively new method of collecting lung tissue for analysis — safely and successfully helps to provide a definitive sarcoidosis diagnosis when the usual and less-invasive diagnostic tools are insufficient, a Portuguese study suggests. The study, “Diagnostic yield and safety of transbronchial cryobiopsy…
Veru Completes Enrollment for Zuclomiphene Citrate Trial for ADT-Induced Hot Flashes in PC
This post was originally published on this site Veru Healthcare has completed patient enrollment for its Phase 2 clinical trial evaluating the use of zuclomiphene citrate (VERU-944) for the treatment of hot flashes in men receiving hormone therapy for prostate cancer. Hot flashes are experienced by about 80% of men on androgen deprivation therapy (ADT). ADT…
$15M Investment Helps Secure Funding for Phase 2 Trial of T3D-959 for Alzheimer’s
This post was originally published on this site T3D Therapeutics has secured the needed funding to move forward with its Phase 2 trial testing T3D-959 as a potential treatment for people with mild-to-moderate Alzheimer’s disease. The total funding includes $15 million from an investor, in addition to a $9 million award from the National Institute…