This post was originally published on this site A U.S. Department of Health and Human Services grant will fund research at two universities into whether an ultrasound technology might be more effective than mammography at detecting breast cancer, particularly in younger people. At present, mammography is most often used to screen for and diagnose breast cancers.…
Conditions
Conditions
FDA Grants N-803 Combo Breakthrough Therapy Status for Non-Muscle Invasive Bladder Cancer
This post was originally published on this site The U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to ImmunityBio‘s interleukin-15 (IL-15) agonist N-803, in combination with Bacillus Calmette-Guerin (BCG) for the treatment of non-muscle invasive bladder carcinoma in situ (CIS) that does not respond to BCG treatment alone. The designation is intended…
Lighter Days Are Around the Corner
This post was originally published on this site “Oh, by the way,” she said nonchalantly as I entered the room. “Your scans are clear.” “I’m sorry, what?” I stuttered in disbelief. Just like that, in a matter of seconds, my oncologist revealed the news I had waited, hoped, and prayed over a year for. Four…
Subgroup of Active T-cells Linked to Worse Disease in Sarcoidosis, Study Reports
This post was originally published on this site The lungs of patients with sarcoidosis are burdened with a more active subset of immune T-cells, called mucosal-associated invariant T (MAIT) cells, a study reports. The activity of these MAIT cells correlates with worse disease, supporting their potential as therapeutic targets, the researchers said. The study, “Activation…
Nuplazid Lowers Dementia-related Psychosis Relapse Risk by Nearly 3 Times, HARMONY Study Shows
This post was originally published on this site People with Alzheimer’s and other dementias treated with Nuplazid (pimavanserin) in a Phase 3 trial were almost three times less likely to have a psychosis relapse — a worsening of delusions and hallucinations — than others, HARMONY trial data show. HARMONY met its main goal, significantly lowering the…
Orencia Given FDA’s Breakthrough Status as Treatment to Prevent Graft-versus-Host Disease After Stem Cell Transplant
This post was originally published on this site Bristol-Myers Squibb‘s arthritis medicine Orencia (abatacept) has been named Breakthrough Therapy by the U.S. Food and Drug Administration for the prevention of acute graft-versus-host disease (GvHD) in patients who received a stem cell transplant from an unrelated donor, the company has announced. The designation intends to accelerate…
Venclexta-Darzalex Combos Show Strong Response Rates in Multiple Myeloma Trial, Early Data Show
This post was originally published on this site Adding the antibody Darzalex (daratumumab) to Venclexta (venetoclax), a lymphoma and leukemia treatment, is a promising approach for multiple myeloma patients who failed prior treatment, particularly those with a common genetic abnormality called t(11;14), new Phase 1/2 data show. The combination reduced tumor burden in nearly all — 92%…
Cancer Research Teams Working to Identify Early Biomarkers of Ovarian Cancer
This post was originally published on this site With a $544,360 developmental grant from the U.S. Department of Defense (DoD), four research teams are joining efforts to identify biomarkers of ovarian cancer with a goal of detecting the disease earlier or before it even develops. The collaboration, named DoD and SPORE Ovarian Cancer Omics Consortium,…
Lower Prostate Cancer Risk in Diabetics Likely Due to Fewer Biopsies, Not Medications, Study Says
This post was originally published on this site Common treatments for diabetes don’t appear to mask or reduce levels of a prostate cancer marker in the blood. Rather, the lower rates of prostate cancer detected in men with diabetes might be because they are less likely to undergo prostate biopsies, a large population-based study from…
Dutch Researchers Develop Apps to Help Caregivers of Dementia Patients
This post was originally published on this site Researchers at Maastricht University Medical Center in the Netherlands have developed two online apps to improve the lives of people who care for dementia patients, and will soon create one for patients themselves. One app provides caregivers with information they can use to achieve balance in their lives. Those…
FDA Approves FoundationOne CDx as Companion Diagnostic Test for Piqray Treatment
This post was originally published on this site The U.S. Food and Drug Administration (FDA) has approved Foundation Medicine’s FoundationOne CDx as a companion diagnostic test for identifying advanced breast cancer patients with a PIK3CA mutation suitable for treatment with Piqray (alpelisib). Piqray was approved in May, in combination with Faslodex (fulvestrant), for postmenopausal women and…
Single-Blinded Trial Design Prevents Patients From Withdrawing Prematurely, Analysis Shows
This post was originally published on this site BeyondSpring’s single-blinded trial design, in which patients are unaware of the treatment they receive, effectively prevented participants from prematurely withdrawing from the company’s DUBLIN-3 study due to dissatisfaction with their treatment allocation, an analysis shows. The findings were presented in a poster, titled “Validation of a Single-Blinded…











